Async-first compounded GLP-1 with a rarity for this list — free health coaching — at a flat one-price-all-doses rate. Fast and friendly up front; the strict, non-refundable fine print is the trade-off.
Trimi Health
Ranked #3 · Grade B+
Rx-Readiness88:100
The price-first partner: some of the lowest flat, all-inclusive compounded pricing we track, nationwide and async — strong if the monthly number is your deciding factor and you read the annual-prepay fine print.
Strut Health
Ranked #12 · Grade B−
Rx-Readiness81:100
The async, needle-optional value play: oral or injectable semaglutide and tirzepatide from a low starting price, no video visit, ~3 days to a script — listed with its February 2026 FDA warning letter in plain view.
Telos Rx
Ranked #5 · Grade B
Rx-Readiness86:100
A fast, fully async start with a needle-free sublingual tirzepatide option and — a genuine upgrade since our last check — flat pricing stated in writing. The catch is a state list it still won't publish.
Rx.com
Ranked #9 · Grade B−
Rx-Readiness82:100
The whole price table before you hand over a detail: $175/mo semaglutide with no commitment, flat at every dose. The advertised $146 is $875 prepaid for six months — and nothing renews on its own.
Renlo Health
Ranked #7 · Grade B
Rx-Readiness85:100
One flat monthly charge with everything genuinely inside it — $199 and $269, no membership or consult fee — plus a published “prescribed today, delivered in two days.”
Science & Co
Ranked #16 · Grade C
Rx-Readiness79:100
It shows both prices at once and says which is which: $149/mo with no commitment, $79 on a twelve-month plan. Brand-name is listed, but all three pages say coming soon.
Pepti
Ranked #21 · Grade C
Rx-Readiness77:100
Pepti publishes the lowest semaglutide price in this entire roster — $99 a month, flat at every titration dose, with the medication, physician review, shipping, refill management and unlimited messaging with your prescribing doctor all inside it. Tirzepatide is $199 on the same all-in, flat-at-every-dose basis. That number is low enough to deserve skepticism, so it is worth saying exactly where it comes from: Pepti states it on a dedicated cost page, repeats it in its FAQ ('we keep pricing flat and transparent at $99/mo all-in'), and prices the comparison against Hims, Henry Meds and Mochi on the same page. It names two prescribing physicians and says its medication is compounded by FDA-registered 503A or 503B pharmacies, though it never names which. The real limits are reach and format: it ships to 36 states rather than 50, it is cash-pay only and bills no insurance, and its needle-free oral GLP-1/GIP drops cost $349 — well above its own injection.
The Edit
Ranked #11 · Grade B−
Rx-Readiness82:100
The Edit is one of the very few providers on this page that names both the medical practice writing your prescription and the pharmacy compounding it — Arora Health & Aesthetics, LLC and The Pharmacy Hub — rather than gesturing at 'licensed US providers'. Compounded semaglutide is $209 a month and tirzepatide $309, the same price at every dose, with the prescription, all injection supplies, the clinician visit and temperature-controlled two-day shipping inside that one number and no membership fee on top. First orders are $100 off, and three- and six-month plans bring the per-month equivalent down to $192 and $178 for semaglutide. It covers all 50 states and, unusually for this market, runs a complete Spanish-language version of the site rather than a machine-translated shim. The limits are real but narrow: it is compounded-only, so there is no FDA-approved Wegovy or Zepbound here, and there is no postpartum, breastfeeding or PCOS guidance anywhere on the site.