ShedRx
Ranked #17 · Grade C
Rx-Readiness79:100
The widest menu on this list — injections, lozenges, drops and a brand-name lane — with a flat price that genuinely holds as your dose climbs. The catch is the exit: every plan locks you in for two months.
Trimi Health
Ranked #3 · Grade B+
Rx-Readiness88:100
The price-first partner: some of the lowest flat, all-inclusive compounded pricing we track, nationwide and async — strong if the monthly number is your deciding factor and you read the annual-prepay fine print.
Compounded semaglutide from $129 a month and tirzepatide from $199, held at the same price at every dose, plus a separate microdose line from $109 for anyone who wants a gentler metabolic effect rather than maximum weight loss. Lttl covers all 50 states and Washington D.C., says it prescribes and ships within 48 hours, and attributes compounding to U.S.A.-licensed pharmacies it does not name. The catalog runs well past weight loss into NAD+, sermorelin, glutathione and B12 from $79, so read the longevity menu as a separate business from the GLP-1 you came for. Prices are published as starting points rather than a single rate, and the first-order discount of up to $140 is promotional.
The Edit
Ranked #11 · Grade B−
Rx-Readiness82:100
The Edit is one of the very few providers on this page that names both the medical practice writing your prescription and the pharmacy compounding it — Arora Health & Aesthetics, LLC and The Pharmacy Hub — rather than gesturing at 'licensed US providers'. Compounded semaglutide is $209 a month and tirzepatide $309, the same price at every dose, with the prescription, all injection supplies, the clinician visit and temperature-controlled two-day shipping inside that one number and no membership fee on top. First orders are $100 off, and three- and six-month plans bring the per-month equivalent down to $192 and $178 for semaglutide. It covers all 50 states and, unusually for this market, runs a complete Spanish-language version of the site rather than a machine-translated shim. The limits are real but narrow: it is compounded-only, so there is no FDA-approved Wegovy or Zepbound here, and there is no postpartum, breastfeeding or PCOS guidance anywhere on the site.
Trellis Vitality
Ranked #13 · Grade B−
Rx-Readiness81:100
Trellis Vitality is the cheapest genuinely-disclosed option on this page: $150 a month for compounded semaglutide and $199 for tirzepatide, month to month, with every dosage available at the same price and no membership fee, no consult fee and a $0 assessment. Commit for three or six months and those fall to $140/$133 and $189/$179. It names the pharmacy that compounds the medication — Vials Rx, described as a US state-licensed, cGMP-compliant facility — which is the disclosure most of its cheaper competitors skip, and it covers all 50 states with board-certified clinicians reviewing intake. The caveats are about what it doesn't sell and doesn't say. There is no FDA-approved brand option, no oral formulation, and none of its pricing appears on the homepage at all — you have to reach the GLP-1 product page to find a single number, which makes it look more opaque than it actually is. There is also no postpartum, breastfeeding or PCOS content anywhere.
AurenRx
Ranked #4 · Grade B
Rx-Readiness86:100
AurenRx names both the practice that prescribes and the pharmacy that compounds, with addresses — Wasef Health, PC c/o Michael Wasef MD in Pinellas Park, Florida, and VialsRX in Houston, Texas — and the prescriber's details match the federal NPI registry exactly. It charges the same for either molecule, which is genuinely unusual: $259 a month on a recurring plan or $299 with no commitment, for semaglutide or tirzepatide alike, plus a low-and-slow microdose track at $229/$250. Everything is included in that price, the online visit is free, and the LegitScript badge it displays is real. The problem is its own front page. AurenRx advertises its GLP-1 and Microdose programs at 'from $129/mo' on the homepage, while the cheapest thing you can actually buy on the product page is $229 — nothing costs $129. That is not a promotion that expired or a plan you have to hunt for; it is roughly half the real price, sitting on the page most readers see first.
Dr. Medical Health
Ranked #22 · Grade C
Rx-Readiness76:100
Compounded semaglutide at $199 a month and tirzepatide at $299, the same price at every dose, and the daily tablet costs the same as the injection on both — all of it on an open pricing page you reach without a quiz. Brand-name prices are published too, which is rare: Wegovy $999, Ozempic $899, Mounjaro $999, cash. Two things to know before you enter a card. The badge at the top of every page says no subscription, and its own FAQ then asks whether you can cancel your subscription and tells you to call before your next billing date — so it does recur, whatever the badge says. And nothing anywhere on the site says how many weeks of medication one $199 charge actually buys. It ships to all 50 states, and it carries a June 2026 FDA warning letter for false or misleading claims, which it has since fixed.
FitFlow
Ranked #23 · Grade C
Rx-Readiness76:100
Flat at every dose - $99 semaglutide, $134 tirzepatide, all fifty states - which makes the annual math trivial. The site never names its operating company.
Renlo Health
Ranked #7 · Grade B
Rx-Readiness85:100
One flat monthly charge with everything genuinely inside it — $199 and $269, no membership or consult fee — plus a published “prescribed today, delivered in two days.”