Telos Rx
Ranked #5 · Grade B
Rx-Readiness86:100
A fast, fully async start with a needle-free sublingual tirzepatide option and — a genuine upgrade since our last check — flat pricing stated in writing. The catch is a state list it still won't publish.
Async-first compounded GLP-1 with a rarity for this list — free health coaching — at a flat one-price-all-doses rate. Fast and friendly up front; the strict, non-refundable fine print is the trade-off.
Strut Health
Ranked #10 · Grade B−
Rx-Readiness81:100
The async, needle-optional value play: oral or injectable semaglutide and tirzepatide from a low starting price, no video visit, ~3 days to a script — listed with its February 2026 FDA warning letter in plain view.
Trimi Health
Ranked #3 · Grade B+
Rx-Readiness88:100
The price-first partner: some of the lowest flat, all-inclusive compounded pricing we track, nationwide and async — strong if the monthly number is your deciding factor and you read the annual-prepay fine print.
Bodybuilding Health+
Ranked #12 · Grade C
Rx-Readiness79:100
Bodybuilding Health+ does the disclosure part better than most of this market and the branding part more loosely. It names four compounding pharmacies outright with phone numbers, and it names two lead physicians with their NPI numbers — both of whom check out as active MDs in the federal registry. Pricing is flat at every dose and public before any intake: $179 a month for compounded semaglutide and $209 for tirzepatide, dropping to $139 and $159 only if you buy a year up front. The looser part is the name. The operator is Dynamo Group LLC of Boca Raton, not Bodybuilding.com, and the 'trusted by millions since 1999' line on the page is the licensor's heritage rather than the clinic's. It's compounded-only, so there's no FDA-approved Wegovy or Zepbound route, the bundle discounts come with no published refund terms, and a prominent '4.8 (200+ reviews)' badge sits above a Trustpilot widget I couldn't verify because Trustpilot blocks automated checks.
Pepti
Ranked #17 · Grade C
Rx-Readiness77:100
Pepti publishes the lowest semaglutide price in this entire roster — $99 a month, flat at every titration dose, with the medication, physician review, shipping, refill management and unlimited messaging with your prescribing doctor all inside it. Tirzepatide is $199 on the same all-in, flat-at-every-dose basis. That number is low enough to deserve skepticism, so it is worth saying exactly where it comes from: Pepti states it on a dedicated cost page, repeats it in its FAQ ('we keep pricing flat and transparent at $99/mo all-in'), and prices the comparison against Hims, Henry Meds and Mochi on the same page. It names two prescribing physicians and says its medication is compounded by FDA-registered 503A or 503B pharmacies, though it never names which. The real limits are reach and format: it ships to 36 states rather than 50, it is cash-pay only and bills no insurance, and its needle-free oral GLP-1/GIP drops cost $349 — well above its own injection.
The Edit
Ranked #9 · Grade B−
Rx-Readiness82:100
The Edit is one of the very few providers on this page that names both the medical practice writing your prescription and the pharmacy compounding it — Arora Health & Aesthetics, LLC and The Pharmacy Hub — rather than gesturing at 'licensed US providers'. Compounded semaglutide is $209 a month and tirzepatide $309, the same price at every dose, with the prescription, all injection supplies, the clinician visit and temperature-controlled two-day shipping inside that one number and no membership fee on top. First orders are $100 off, and three- and six-month plans bring the per-month equivalent down to $192 and $178 for semaglutide. It covers all 50 states and, unusually for this market, runs a complete Spanish-language version of the site rather than a machine-translated shim. The limits are real but narrow: it is compounded-only, so there is no FDA-approved Wegovy or Zepbound here, and there is no postpartum, breastfeeding or PCOS guidance anywhere on the site.
Coivas
Ranked #41 · Grade C
Rx-Readiness69:100
Flat compounded pricing with the post-introductory number actually printed: $149 a month for semaglutide and $229 for tirzepatide, the same at every dose, after intro rates of $119 and $199. For planning purposes that flatness is the useful part — a titration step-up does not change the bill, so the number you budget in month one is the number in month six. All 50 states, and consultation, prescription, medication, shipping and support are inside the price. Watch the word "from" on every figure: the site says dosage and titration can move what you pay.
Trellis Vitality
Ranked #11 · Grade B−
Rx-Readiness81:100
Trellis Vitality is the cheapest genuinely-disclosed option on this page: $150 a month for compounded semaglutide and $199 for tirzepatide, month to month, with every dosage available at the same price and no membership fee, no consult fee and a $0 assessment. Commit for three or six months and those fall to $140/$133 and $189/$179. It names the pharmacy that compounds the medication — Vials Rx, described as a US state-licensed, cGMP-compliant facility — which is the disclosure most of its cheaper competitors skip, and it covers all 50 states with board-certified clinicians reviewing intake. The caveats are about what it doesn't sell and doesn't say. There is no FDA-approved brand option, no oral formulation, and none of its pricing appears on the homepage at all — you have to reach the GLP-1 product page to find a single number, which makes it look more opaque than it actually is. There is also no postpartum, breastfeeding or PCOS content anywhere.