Telos Rx
Ranked #5 · Grade B
Rx-Readiness86:100
A fast, fully async start with a needle-free sublingual tirzepatide option and — a genuine upgrade since our last check — flat pricing stated in writing. The catch is a state list it still won't publish.
Enhance MD
Ranked #27 · Grade C
Rx-Readiness72:100
The oversight-forward compounder: labs and a live provider visit bundled into every plan, with a gentle microdosing lane — the catch is that the low '$212' headline you'll see quoted is the 12-month prepay rate, not the $249 you'd pay month to month.
Async-first compounded GLP-1 with a rarity for this list — free health coaching — at a flat one-price-all-doses rate. Fast and friendly up front; the strict, non-refundable fine print is the trade-off.
Strut Health
Ranked #10 · Grade B−
Rx-Readiness81:100
The async, needle-optional value play: oral or injectable semaglutide and tirzepatide from a low starting price, no video visit, ~3 days to a script — listed with its February 2026 FDA warning letter in plain view.
Trimi Health
Ranked #3 · Grade B+
Rx-Readiness88:100
The price-first partner: some of the lowest flat, all-inclusive compounded pricing we track, nationwide and async — strong if the monthly number is your deciding factor and you read the annual-prepay fine print.
RxSpan MD
Ranked #8 · Grade B−
Rx-Readiness82:100
RxSpan MD is a genuinely well-disclosed service wrapped in marketing that undercuts it. The disclosure: four compounding pharmacies named with phone numbers, two lead physicians named with NPI numbers that verify as active MDs, flat pricing posted before any intake, both compounded and real FDA-approved brand GLP-1s on one platform, and oral capsules for anyone who won't inject. Compounded semaglutide is $249 a month and tirzepatide $329, with brand Zepbound at $1,069, Ozempic at $1,299 and Wegovy at $1,349. The marketing is the problem. Its testimonials still name a different company — one patient describes what she 'expected from CareGLP' — and the doctors quoted in them are not the clinicians the same page names as its medical team. The homepage is built around a board-certified plastic surgeon who founded the practice but is licensed in California only and isn't the prescriber. Its compounded prices also sit above the roster median, and the oral capsules cost the same or more than the injections.
AurenRx
Ranked #4 · Grade B
Rx-Readiness86:100
AurenRx names both the practice that prescribes and the pharmacy that compounds, with addresses — Wasef Health, PC c/o Michael Wasef MD in Pinellas Park, Florida, and VialsRX in Houston, Texas — and the prescriber's details match the federal NPI registry exactly. It charges the same for either molecule, which is genuinely unusual: $259 a month on a recurring plan or $299 with no commitment, for semaglutide or tirzepatide alike, plus a low-and-slow microdose track at $229/$250. Everything is included in that price, the online visit is free, and the LegitScript badge it displays is real. The problem is its own front page. AurenRx advertises its GLP-1 and Microdose programs at 'from $129/mo' on the homepage, while the cheapest thing you can actually buy on the product page is $229 — nothing costs $129. That is not a promotion that expired or a plan you have to hunt for; it is roughly half the real price, sitting on the page most readers see first.
Pepti
Ranked #17 · Grade C
Rx-Readiness77:100
Pepti publishes the lowest semaglutide price in this entire roster — $99 a month, flat at every titration dose, with the medication, physician review, shipping, refill management and unlimited messaging with your prescribing doctor all inside it. Tirzepatide is $199 on the same all-in, flat-at-every-dose basis. That number is low enough to deserve skepticism, so it is worth saying exactly where it comes from: Pepti states it on a dedicated cost page, repeats it in its FAQ ('we keep pricing flat and transparent at $99/mo all-in'), and prices the comparison against Hims, Henry Meds and Mochi on the same page. It names two prescribing physicians and says its medication is compounded by FDA-registered 503A or 503B pharmacies, though it never names which. The real limits are reach and format: it ships to 36 states rather than 50, it is cash-pay only and bills no insurance, and its needle-free oral GLP-1/GIP drops cost $349 — well above its own injection.
The Edit
Ranked #9 · Grade B−
Rx-Readiness82:100
The Edit is one of the very few providers on this page that names both the medical practice writing your prescription and the pharmacy compounding it — Arora Health & Aesthetics, LLC and The Pharmacy Hub — rather than gesturing at 'licensed US providers'. Compounded semaglutide is $209 a month and tirzepatide $309, the same price at every dose, with the prescription, all injection supplies, the clinician visit and temperature-controlled two-day shipping inside that one number and no membership fee on top. First orders are $100 off, and three- and six-month plans bring the per-month equivalent down to $192 and $178 for semaglutide. It covers all 50 states and, unusually for this market, runs a complete Spanish-language version of the site rather than a machine-translated shim. The limits are real but narrow: it is compounded-only, so there is no FDA-approved Wegovy or Zepbound here, and there is no postpartum, breastfeeding or PCOS guidance anywhere on the site.