MadeMed
Ranked #49 · Grade C
Rx-Readiness68:100
A flat $239/mo semaglutide, $399/mo tirzepatide, no-video intake with free overnight shipping — but it's only live in 23 states, and most big population centers aren't on the list.
Gala Health
Ranked #6 · Grade B
Rx-Readiness85:100
A flat $179 for either molecule with a genuinely gentle microdosing tier — a reasonable, all-doses-included partner if you can live with a yearly plan and a pharmacy it doesn't name.
Aurelius Health Group
Ranked #104 · Grade C
Rx-Readiness61:100
A one-product shop — compounded tirzepatide microdosing only, $89 the first month then $199/mo all-in, no live video visit described anywhere in the flow, and unusually candid on-site that the trial evidence for microdosing specifically is thin — but there's no semaglutide option at all, and no individual physician, pharmacy, or state list named anywhere on the site checked.
WeightlessRx
Ranked #67 · Grade C
Rx-Readiness66:100
A no-membership-fee, quarterly-billed program — $167/mo semaglutide, $267/mo tirzepatide — bundling a GLP-1 fitness app, meal plans, and 1-on-1 nutrition coaching that most compounded-only competitors don't offer. It also publishes its own named comparison against Ro, Mochi Health, TrimRx, and Hims, an unusually direct move for this category.
FitFlow
Ranked #19 · Grade C
Rx-Readiness76:100
Flat at every dose - $99 semaglutide, $134 tirzepatide, all fifty states - which makes the annual math trivial. The site never names its operating company.
Collective
Ranked #135 · Grade C
Rx-Readiness59:100
The lowest medication price on this roster, and a headline that still leaves out a required charge. Compounded semaglutide is $59 a month and tirzepatide $69, flat at every dose and cancellable at any time — both requiring a $199 annual membership the pricing line never mentions. Counted properly the first year is $907 for semaglutide, about $76 a month, and $1,027 for tirzepatide, about $86, which remains among the cheapest anywhere even after the fee. It is operated by Health For Everyone Inc., trading as CollectiveOS, and positioned on being brought to you by the founder of Thrive Market and on GLP-1s without the 500% markup. There is a 21-day free trial before the membership charge, after which the fee is non-refundable with no partial periods returned. The compounding pharmacies are never named, no state list is published, and no time to first dose is given.
Trellis Vitality
Ranked #11 · Grade B−
Rx-Readiness81:100
Trellis Vitality is the cheapest genuinely-disclosed option on this page: $150 a month for compounded semaglutide and $199 for tirzepatide, month to month, with every dosage available at the same price and no membership fee, no consult fee and a $0 assessment. Commit for three or six months and those fall to $140/$133 and $189/$179. It names the pharmacy that compounds the medication — Vials Rx, described as a US state-licensed, cGMP-compliant facility — which is the disclosure most of its cheaper competitors skip, and it covers all 50 states with board-certified clinicians reviewing intake. The caveats are about what it doesn't sell and doesn't say. There is no FDA-approved brand option, no oral formulation, and none of its pricing appears on the homepage at all — you have to reach the GLP-1 product page to find a single number, which makes it look more opaque than it actually is. There is also no postpartum, breastfeeding or PCOS content anywhere.
GobyMeds
Ranked #88 · Grade C
Rx-Readiness63:100
A 3-month starter-bundle model — $99/mo semaglutide, $133/mo tirzepatide, medication plus shipping, consult and an injection kit included — serving all 50 states with no membership fees.
The Edit
Ranked #9 · Grade B−
Rx-Readiness82:100
The Edit is one of the very few providers on this page that names both the medical practice writing your prescription and the pharmacy compounding it — Arora Health & Aesthetics, LLC and The Pharmacy Hub — rather than gesturing at 'licensed US providers'. Compounded semaglutide is $209 a month and tirzepatide $309, the same price at every dose, with the prescription, all injection supplies, the clinician visit and temperature-controlled two-day shipping inside that one number and no membership fee on top. First orders are $100 off, and three- and six-month plans bring the per-month equivalent down to $192 and $178 for semaglutide. It covers all 50 states and, unusually for this market, runs a complete Spanish-language version of the site rather than a machine-translated shim. The limits are real but narrow: it is compounded-only, so there is no FDA-approved Wegovy or Zepbound here, and there is no postpartum, breastfeeding or PCOS guidance anywhere on the site.