Compounded semaglutide from $129 a month and tirzepatide from $199, held at the same price at every dose, plus a separate microdose line from $109 for anyone who wants a gentler metabolic effect rather than maximum weight loss. Lttl covers all 50 states and Washington D.C., says it prescribes and ships within 48 hours, and attributes compounding to U.S.A.-licensed pharmacies it does not name. The catalog runs well past weight loss into NAD+, sermorelin, glutathione and B12 from $79, so read the longevity menu as a separate business from the GLP-1 you came for. Prices are published as starting points rather than a single rate, and the first-order discount of up to $140 is promotional.
FitFlow
Ranked #19 · Grade C
Rx-Readiness76:100
Flat at every dose - $99 semaglutide, $134 tirzepatide, all fifty states - which makes the annual math trivial. The site never names its operating company.
Trellis Vitality
Ranked #11 · Grade B−
Rx-Readiness81:100
Trellis Vitality is the cheapest genuinely-disclosed option on this page: $150 a month for compounded semaglutide and $199 for tirzepatide, month to month, with every dosage available at the same price and no membership fee, no consult fee and a $0 assessment. Commit for three or six months and those fall to $140/$133 and $189/$179. It names the pharmacy that compounds the medication — Vials Rx, described as a US state-licensed, cGMP-compliant facility — which is the disclosure most of its cheaper competitors skip, and it covers all 50 states with board-certified clinicians reviewing intake. The caveats are about what it doesn't sell and doesn't say. There is no FDA-approved brand option, no oral formulation, and none of its pricing appears on the homepage at all — you have to reach the GLP-1 product page to find a single number, which makes it look more opaque than it actually is. There is also no postpartum, breastfeeding or PCOS content anywhere.
Join Polly
Ranked #64 · Grade C
Rx-Readiness66:100
A recently-rebranded provider (formerly Piper, now Join Polly) with a flat, dose-independent price for both molecules — $135/mo semaglutide, $199/mo tirzepatide — and one of the few among the providers we track to publicly name its compounding pharmacies (Hallandale Pharmacy, VialsRx).
NewSelf
Ranked #36 · Grade C
Rx-Readiness70:100
FDA warning letter #721472 (Feb. 2026), which names newself.com. A flat, dose-independent price for both molecules — $99.97/mo semaglutide, $144.49/mo tirzepatide, same price at every dose — nationwide, though it requires 3 months upfront.
Mondae
Ranked #28 · Grade C
Rx-Readiness72:100
Mondae is built for someone who wants the decisions made up front and then left alone. Price, plan length and — unusually — which of six named compounding pharmacies fills the prescription are all settled before intake, the questionnaire is asynchronous with no video call to book, and it serves all 50 states. The rate is $115 a month for compounded semaglutide and $145 for compounded tirzepatide, with no membership fee stacked on top and no increase as you titrate: 'your dose may increase, but your price is fixed.' For a working parent that predictability is the whole point, because a dose-priced plan can quietly double between a starting and a maintenance dose. The pharmacy disclosure is the standout — Boudreaux, Rush, Hallandale, Greenwich, Align and VialsRx, named and selectable, where most of this category names none — with the honest caveat that Mondae itself flags: each ships to different states and formulations 'may contain additional additives.' Both prices were verified from a rendered page rather than a marketing card, because the raw HTML ships a '$NNN' placeholder, and they agree with the homepage card and the page's own structured data. What is absent is routine: no named clinician behind the contracted Bask Telehealth network, no labs, no refunds once medication is dispensed, and nothing addressing postpartum recovery, breastfeeding or PCOS.
Coivas
Ranked #41 · Grade C
Rx-Readiness69:100
Flat compounded pricing with the post-introductory number actually printed: $149 a month for semaglutide and $229 for tirzepatide, the same at every dose, after intro rates of $119 and $199. For planning purposes that flatness is the useful part — a titration step-up does not change the bill, so the number you budget in month one is the number in month six. All 50 states, and consultation, prescription, medication, shipping and support are inside the price. Watch the word "from" on every figure: the site says dosage and titration can move what you pay.
NextMeds
Ranked #50 · Grade C
Rx-Readiness68:100
Compounded semaglutide at $79 a month and tirzepatide at $119, month to month, with no dose-based increase and — checked in its own checkout data rather than taken on trust — a renewal price identical to the joining price. That last part is rarer than it should be. Two things the homepage will not tell you. The $49 and $99 it advertises are the twelve-month totals divided by twelve, not a monthly rate you can start on, and the countdown beside them is not a real deadline: it read August 15th and then August 20th within the same hour. The larger caveat is corporate. NextMeds is operated by Trinity HealthCare Supply, LLC, which also runs Lean Meds, altRx and Trinity Meds, and that operator holds an open FDA warning letter.
LumiMeds
Ranked #98 · Grade C
Rx-Readiness62:100
A named-Medical-Director program licensed in all 50 states, from $99/mo semaglutide and $183/mo tirzepatide, with no membership required — but it carries a 2025 FDA warning letter over how it described its compounded medication, and both prices are 'From' starting prices rather than a guaranteed working-dose rate.